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Immunomodulators

Immunomodulators

 

A Drug that is used for its effect on the immune system is an immunomodulator. Immunomodulator is safer and superior alternates to steroids.

There are two types of such drugs based on their effects:

Immunosuppressants
Immunostimulators

Immunosuppressants reduce the activation or efficacy of the immune system.

Immunosuppressants are generally given to prevent body from rejecting an organ transplant or for treating auto immune diseases like rheumatoid arthritis, crohn’s disease, generalised eczematous disorders, paradoxical exerbation of chronic urticaria etc.

Immunostimulants are the drugs which stimulate the immune system by inducing activation or increasing activity of any of its components.

We introduced an anthelmintic Levamisole hydrochloride 150mg. tabs. which is also approved as an immunomodulator by FDA USA in 2005.

In 2011 in its continuous efforts to introduce selective quality medicines we introduced Azathioprine which is approved Drug for prevention of rejection in renal homotransplantations and for refractory, severe rheumatoid arthritis.

Types of Immunomodulators

 

Azawan

Specifications of Azawan

Product Name
AZAWAN Tabs.

Ingredients
Azathioprine 50 mg.

Pack & Special Features
Azawan is in alu-alu pack of 10’s. Box of 10x10’s.
It is a synthetic purine analog derived from 6-mercaptopurine(6-MP).
It is quickly and completely absorbed from G.I tract and does not cross blood brain barrier.
Peak Plasma levels are achieved in two hours and half life of Azawan is approx. 5 hours.
It is generally well tolerated and has favourable therapeutic index.
It is non teratogenic.

Technical Specification
Azathioprine is an imidazolyl derivative of 6-mercaptopurine. Two important enzymes in the metabolism of Azawan are thiopurine s-methyltransferase(TPMT) & xanthine oxidase(XO)

Vapal-150

Specifications of Vapal-150

Product Name
VAPAL-150 Tabs.

Ingredients
Levamisole hydrochloride 150mg.

Pack & Special Features
VAPAL-150 is available in blister of 1’s , colour sunset yellow.
VAPAL-150 is an anthelmintic and FDA approved immunomodulator.
It is rapidly absorbed from GI Tract and attains peak plasma concentration of 0.12mg/ml in 1.5 to 2 hours.
Plasma elimination half life of VAPAL is 3-6 hours.
It is simple, safe and fairly effective remedy for controlling activity of disease process in Vitiligo.

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